Premier League leaders Chelsea beat London rivals Arsenal 2-1 while Tottenham Hotspur ended their Old Trafford hoodoo and beat Manchester United 3-2 there for the first time since 1989 to leave Chelsea three points clear on Saturday.
Danny Murphy converted a second-half penalty to give Liverpool a 1-0 victory at Old Trafford.
Mauricio Pochettino has left his job as Chelsea manager by mutual consent, the Premier League side announced on Tuesday.
Tottenham Hotspur continued their Premier League title push with a 2-0 win over Everton on Wednesday to put them level on points with second-placed champions Manchester United and three behind leaders Manchester City.
Erling Haaland's double put Manchester City within touching distance of an unprecedented fourth successive Premier League title
The shade of the shirt may have changed but Robin van Persie remains a red-hot Dutch master after marking his first Manchester United start with a goal in a 3-2 Premier League win over Fulham on Saturday.
Holders Manchester City will take on RB Leipzig, Red Star Belgrade and Young Boys in Group G.
Manchester United enjoyed a stroll in the spring sunshine on Saturday as they eased to a 2-0 home win over Fulham to open a 10-point lead at the top of the Premier League.
Images from the EPL matches played on Saturday
Images from the EPL matches played on Sunday
Roundup of the Champions League matches played on Wednesday night
News of all that's transpired on and off the football field on Saturday
Arsenal are eighth, seven points adrift of fourth-placed Chelsea, while Norwich remain second from bottom.
Nuno's coaching staff have also been relieved of their duties. The club have not yet announced a replacement but British media reported former Chelsea and Inter Milan boss Antonio Conte is linked.
Manchester United's 3-0 victory over Fulham gave them the top spot in the English premier league.
Manchester United and Liverpool, England's two most successful clubs, will do battle in the third round of the FA Cup after the draw was made on Sunday.
Arsenal head to Manchester United this weekend with manager Arsene Wenger talking of strange times and serenity but he is not referring to the fact his Premier League leaders are the favourites for the first time in many years.
A summary of Saturday's matches in the English Premier League.
Carlos Tevez produced a stunning equaliser before Michael Carrick's late strike earned Manchester United a 2-1 victory at Wigan Athletic Wednesday to move within one point of a third consecutive Premier League title.
British bookmakers William Hill consider Chelsea 9-2 favourites to win the competition for the first time, followed by Barcelona and AC Milan on 11-2.
A controversial goal from Didier Drogba helped Chelsea to a crucial 2-1 victory over Manchester United at Old Trafford on Saturday and leapfrog the champions at the top of the Premier League table.
Arsenal slumped to a last-gasp 2-1 Premier League defeat at relegation-threatened Brighton & Hove Albion on Saturday in a blow to the London club's chances of securing European football next season. Watford's Craig Dawson grabbed a stoppage-time equaliser with an overhead kick to earn his side a 1-1 draw with Leicester City on Saturday and a vital point in their battle for Premier League survival.
Liverpool won the Champions League under Benitez in 2005 and were runners-up last year, but they have struggled in England.
Meanwhile, Manchester United winger Jesse Lingard says his "heart is at Old Trafford" and negotiations are ongoing over a new deal with the club that will extend a contract that runs out at the end of next season.
Arsenal legends Ray Parlour and Sol Campbell says while it might be difficult for the Gunners to recreate the unbeaten season of 2003-04 they could certainly challenge for the title in the coming season provided the club signs up a couple of good players this season.
Manchester beat Aston Villa 2-0 to slash Chelsea's Premier League lead to six points.
Manchester United lost ground in the English premier league title race at the Riverside Stadium when they lost 3-1 to Middlesbrough on Thursday.
Manchester United's new winger Angel Di Maria will not change the course of their troubled season straight away following his British record transfer from Real Madrid, manager Louis van Gaal said on Tuesday.
News of all that's transpired on and off the football field
Late goals from Nicklas Bendtner and Theo Walcott spared Arsenal's blushes and kept them top of the Premier League in a 2-0 victory over Cardiff City as title rivals Manchester City and Chelsea also won on Wednesday.
With City pulling out and Chelsea set to leave, while Liverpool's players posted a shared Twitter message saying they want no part of the new league, the ESL project looks doomed.
A round-up of Saturday's action in the English Premier League.
Manchester City's stellar season gathered yet more momentum as the runaway English Premier League leaders reached the League Cup semi-finals with a penalty shootout victory at Leicester City.
UEFA issued a strong statement jointly with English, Spanish and Italian leagues and football federations, saying they were ready to use "all measures" to confront any breakaway and saying any participating clubs would be banned from domestic leagues, such as the Premier League.
Manchester United beat Wigan to extend their lead atop the EPL after Chelsea were held by Reading.
The difference between this side and the under-achieving teams towards the end of Wenger's reign is their experience. Martinelli made his debut in 2019 while Saka has been a regular since the 2019-20 campaign.
News of all that's transpired on and off the football field